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A systematic review has found that capillary refill time of three seconds or longer is an important warning sign for serious illness and risk of death in children.

Published in PLOS OneThe Diagnostic Value of Capillary Refill Time for Detecting Serious Illness in Children: A Systematic Review and Meta-Analysis  is the first comprehensive and systematic assessment of the diagnostic value of the CRT test for a range of serous outcomes in children worldwide. The research was led by Dr Susannah Fleming, a research fellow in the University of Oxford’s Nuffield Department of Primary Care Health Sciences. Susannah was a SPCR Fellow from 2010 to 2013 during which time the research was undertaken. The research has been included as a NIHR Signal by the NIHR Dissemination Centre.

 Read more.

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