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FR 12

Title Principal Investigator Start date End date
Improving identification of familial hypercholesterolaemia in primary care using a new case ascertainment tool (FAMCAT) Nadeem Qureshi 1 July 2016 30 December 2018
Developing and evaluating a measure of inappropriate polypharmacy in primary care Rupert Payne 1 July 2016 30 June 2018
Quantifying severity of chronic conditions in English Primary Care using the Clinical Practice Research Datalink Evan Kontopantelis 4 July 2016 5 July 2019
OPtimising Treatment for MIld Systolic hypertension in the Elderly (OPTiMISE) James Sheppard 1 October 2016 31 May 2019
Feasibility study of Pelargonium sidoides root extract EPs®7630 (Kaloba®) for lower respiratory tract infection in adults Michael Moore 1 January 2017 31 December 2018

FR 11

Title Principal Investigator Start date End date
Patient-led non-pharmacological management of ACuTe FLAREs of knee osteoarthritis in primary care settings: a feasibility and pilot study 1 April 2016 31 March 2017
IMprovIng access to DemeNtiA caRE for BriTish ethnic minorities Waquas Waheed 1 April 2016 30 September 2016
Exploring the views of key stakeholders on an intervention aimed at improving the safety of prescribing of GP Associates in training Richard Knox 1 April 2016 31 March 2017
DiSCeRN - eviDence Synthesis of Clinical Study reports for NOACs (DiSCeRN - phase 1) Kamal Mahtani 1 April 2016 30 September 2016
The Evidence of Effects Page: Refinement of a tool for optimising evidence-based informed treatment decisions In Clinical practice (The EEPIC-1 study) David Nunan 1 April 2016 31 March 2017
An examination of STI testing influences for young people in primary care Lorraine McDonagh 1 April 2016 31 January 2017
A risk prediction tool to identify pregnant women at high risk of postnatal depression 1 February 2016 31 January 2017
A systematic review of the measurement of implementation fidelity in primary care trials Rebecca Barnes 1 July 2016 1 April 2017
Systematic review of community detoxification for alcohol dependency David Kessler 1 April 2016 31 December 2016
Impact of hospital admission upon patterns of primary care prescribing Rupert Payne 1 April 2016 31 March 2017
Identifying the most appropriate treatment for IAPT attendees with depression and co-morbid personality difficulties Katrina Turner 1 April 2016 31 March 2017
The Tip of the Iceberg: Identifying Patients with Heart Failure and Preserved Ejection Fraction (HFpEF) in Primary Care Christi Deaton 2 March 2016 1 September 2016
Identifying patients at raised risk of stroke due to paroxysmal or persistent atrial fibrillation in primary care populations Duncan Edwards 1 April 2016 31 March 2018
Towards person-centred care: development of a patient support needs tool for patients with advanced Chronic Obstructive Pulmonary Disease (COPD) in primary care Morag Farquhar 1 February 2016 31 August 2016
Validation of existing risk prediction models for prostate cancer using data from UK BioBank and EPIC-Norfolk Greg Irving 1 March 2016 28 February 2017
Developing and pre-testing a tailored interactive voice response (IVR) intervention to support adherence to anti-hypertensive medications Katerina Kassavou 1 September 2016 31 March 2017
Exploring patient barriers to the diagnosis of Giant Cell Artheritis in primary care James Prior 1 April 2016 31 March 2017
Illness perceptions and explanatory models in patients with type 2 diabetes and co-morbid depression. Athula Sumathipala 1 April 2016 31 March 2017
Burnout in general practitioners: a systematic review of relationships with patient safety and a feasibility study of the measurement of burnout Maria Panagioti 1 April 2016 31 October 2016
Characterising the primary care population with frailty to better stratify and target healthcare interventions David Reeves 1 April 2016 30 September 2017
Determinants and burden of differing health trajectories in the very old Rachel Duncan 1 September 2016 31 August 2017
Collaborating with patients to improve patient safety in primary care Susan Hrisos 1 January 2016 30 October 2016
Exploring the relationship between frailty, multi-morbidity and the use of healthcare resource by the very old. Louise Robinson 1 April 2016 30 June 2017
Unintended effects of novel oral anticoagulants (NOAC) vs warfarin in real world settings Julia Hippisley-Cox 1 April 2016 31 March 2017
Is systematic identification of Familial Breast Cancer risk more cost-effective than the currently recommended opportunistic approach in primary care? Matthew Jones 1 April 2016 31 December 2016
Trends in NHS prescribing of dual NRT (DNRT) and varenicline in pregnancy and effects on infants Lisa Szatkowski 1 April 2016 31 December 2016
Developing CONSORT guidelines for lay summaries on clinical trials, and evaluating their impact. Ben Goldacre 1 April 2016 31 July 2016
Systematic review to assess the impact of point-of-care tests on patients and healthcare processes Clare Goyder 1 April 2016 31 July 2016
Blood pressure in pregnancy: a discourse analysis of official, informal and online information for pregnant women. Lisa Hinton 1 September 2016 30 November 2016
Availability of withdrawn anorexigenics for sale in search engines Tim Muntinga 1 April 2016 30 March 2017
Development of Primary Care Trial Management System Ly-Mee Yu 1 April 2016 31 March 2017
Exploring primary care patients’ experience of an internet intervention ‘Healthy Paths’ for emotional distress 1 May 2016 30 April 2017
Rosehip for osteoarthritis of hip, hand and knee: A Cochrane review George Lewith 1 April 2016 31 March 2017
Screening for Atrial Fibrillation using Economical and Accurate TechnologY (SAFETY) – a pilot study Mark Lown 1 April 2016 31 March 2017
Experiences of lower limb cellulitis and cellulitis prevention: qualitative interview study Miriam Santer 1 March 2016 30 November 2016
MOVA: Mindfulness in Recurrent Ovarian Cancer – a feasibility study Sam Watts 1 May 2016 30 April 2017
Exploring the use of the Internet as a support tool for older family carers of people with dementia Nathan Davies 1 April 2016 31 March 2017
Patients’ and primary care professionals’ views on, and preferences for, a digital diabetes prevention programme (DDPP) among individuals at high risk of developing diabetes Elizabeth Murray 1 January 2016 31 December 2016

FR 10

Title Principal Investigator Start date End date
Understanding the volume and content of general practice consultations: the 5th National Morbidity Study Chris Salisbury 1 January 2016 31 August 2017
CANDID Paul Little 1 October 2015 30 September 2016
ATAFUTI Michael Moore 1 October 2015 28 February 2016
Deaths and hospital admissions during cold weather: derivation and validation of a tool to help primary care identify vulnerable people Richard Morris 1 March 2016 31 August 2017
Doctors as patients - a qualitative study to explore the barries and facilitators to help - seeking by General Practitioners with mental helth problems: improving access to care Ruth Riley 1 January 2016 28 February 2017
Administrative data to evaluate new models of primary care Martin Roland 1 January 2016 31 December 2017
Harnessing resources from the internet to maximise outcomes from GP consultations (HaRI): a qualitative study Fiona Stevenson 1 January 2016 31 December 2017

FR 9

Title Principal Investigator Start date End date
Can metaphors usefully represent underlying CBT principles for Medically Unexplained Symptoms (MUS), and how acceptable are such generic and MUS specific metaphors to patients and practitioners? Athula Sumathipala 1 October 2015 30 June 2016
The role of systemic inflammatory diseases in long-term morbidity and mortality: a retrospective, matched-cohort study in the Clinical Research Practice Datalink Lorna Clarson 1 October 2015 30 September 2016
The diagnostic and prognostic value of the symptom of shortness of breath in primary care: a cohort study Ying Chen 1 October 2015 30 September 2016
Predicting individual risk of future hip and knee replacement for osteoarthritis Dahi Yu 1 October 2015 30 September 2016
Empowering People to Help Speak Up about Safety (EPHESUS) in Primary Care Sarah Knowles 1 January 2016 30 July 2016
Assessing dementia risk in general practice: a qualitative study of the attitudes and views of patients and the public. Louise Robinson 1 October 2015 30 September 2016
Can a frailty index be used in primary care practice to improve prognostication at the end of life? A multi-method study Barbara Hanratty 1 October 2015 30 September 2016
Keeping active: maintenance of physical activity in older people after an exercise intervention Denise Kendrick 1 October 2015 30 September 2016
Anticholinergic drugs and the risk of dementia: a nested case control study Carol Coupland 1 October 2015 30 September 2016
Implementing diagnostic genetic testing for familial hypercholesterolaemia in primary care: qualitative study Nadeem Qureshi 1 October 2015 30 September 2016
Blood pressure self-monitoring individual patient meta-analysis of registered trials; sub group analyses in a multi-morbid population Katherine Tucker 1 October 2015 30 September 2016
Risk factors for influenza-related complications in children: a retrospective cohort study using linked routinely collected data from the Clinical Practice Research Datalink and National Pandemic Flu Service Kay Wang 1 October 2015 30 September 2016
Evidence synthesis for economic decision models of primary care diagnostics Tom Fanshawe 1 October 2015 31 December 2015
Getting it right for autistic patients: a qualitative study Sara Ryan 1 October 2015 30 June 2016
The Association Between Evidence-Based Medication Use And Unplanned Hospital Admissions: A National Observational Study in Primary Care Kamal Mahtani 1 October 2015 30 September 2016
The development of a digital GP behaviour change intervention to support GPs in the delivery of evidence based practice around the management of PSA screening and active surveillance in primary care Sam Watts 1 April 2016 31 March 2017
Investigating the impact of a short-course MBSR-based mindfulness intervention on patients with difficult-to-manage asthma 1 October 2015 31 March 2016
Southampton communication study (SoCS): managing multiple health concerns Geraldine Leydon 16 November 2015 14 November 2016
UNderstanding medIcal and non-medical anTibiotic prescribing for rEspiratory tract infections in primary care out of hours services: a qualitative analysis Geraldine Leydon 1 October 2015 29 September 2016
Andrographis paniculata for symptomatic relief of lower respiratory tract infection: A Cochrane review George Lewith 1 October 2015 30 September 2016
Assessing dementia risk in general practice: a qualitative study of the attitudes and views of primary care health professionals Greta Rait 1 October 2015 30 June 2016
Assessment of sarcopenia in primary care:identifying potential practical tools for assessment and scope for intervention Goya Wannamethee 1 October 2015 30 April 2016
Process evaluation of the Digital Alcohol Management on Demand (DIAMOND) feasibility randomised controlled trial Fiona Hamilton 1 October 2015 30 September 2016
Online structured education with email facilitation for people with type 2 diabetes: feasibility trial Elizabeth Murray 1 October 2015 30 September 2016
Antidepressants for Insomnia - Cochrane Review Hazel Everitt 1 February 2014 30 October 2014
Children and Adolescents with Musculoskeletal Pain in primary care: CAM-Pain Feasibility Study Kate Dunn 1 October 2015 30 September 2016
Investigation of the factors behind the training choices of junior doctors which result in inadequate recruitment to general practice careers. Sharon Spooner 1 October 2015 31 December 2016
The role of primary care in liver disease: early detection and end of life care? A qualitative study of the perceptions of primary health care professionals Barbara Hanratty 1 October 2015 30 September 2016