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  • 1 March 2016 to 30 November 2016
  • Project No: 319
  • Funding round: FR 11

Background

Cellulitis is a painful bacterial infection of the skin and underlying tissues, commonly affecting the lower leg. Cellulitis can be caused by breaks in the skin, allowing bacteria to get through. Skin breaks can be caused by fungal foot disease (Athlete’s Foot), which is often untreated or un-noticed. Skin breaks can also be caused by inadequate foot care leading to dry, cracked skin.

Approximately a third of people with cellulitis have repeated episodes. The only treatment shown to reduce the risk of recurrence is long-term antibiotics, which can cause antibiotic resistance and side effects.

Aim

We aim to explore different methods for reducing the risk of recurrent cellulitis in order to avoid antibiotic use for this condition. To help us design this study, we will interview people who have had cellulitis to find out more about their views around causation and experiences of preventing recurrence.

Methods

We will ask people to take part in interviews about cellulitis by inviting them through their general practice, through attending hospital for cellulitis or through advertising. Interviews will follow an interview guide to ensure we cover key aims, while also remaining open to exploring the participants’ concerns.

Patient and public involvement

Patients have been involved in the design of this study through the Centre of Evidence-Based Dermatology Patient Panel and Research Design Service.

Implications

We will plan a full-scale trial, based on findings from this study. If effective, these interventions could reduce cellulitis recurrence rates and reduce the use of antibiotics for this painful condition.

Amount awarded: £46,832

Evidence synthesis working group

The collaboration will be conducting 18 high impact systematic reviews, under four workstreams.

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