What over the counter (OTC) products have been evaluated for anxiety in adults aged 18–60? A scoping review.

Rachael Frost, Sayem Uddin, Silvy Mathew, Verity Thomas, Adriana Salame, Sukvinder Kaur Bhamra, Juan Carlos Bazo-Alvarez, Cini Bhanu, Michael Heinrich, Kate Walters

Background Anxiety symptoms and disorders are common in the UK. Whilst waiting for, or alongside, treatments such as anxiolytics or psychological therapies, people often self-manage anxiety symptoms with products purchased over-the-counter (OTC), such as herbal medicines or dietary supplements. However, the evidence for these products is often presented across different reviews and is not easy for patients or healthcare professionals to compare and understand. Aims To determine the nature and size of the evidence base available for these products. Methods A scoping review. CENTRAL, MEDLINE, EMBASE, PsycInfo, and AMED (inception—Dec 2022) were searched for RCTs assessing OTC products in people aged 18–60 with symptoms or a diagnosis of anxiety. Results In total 69 papers assessing a range of products were found, which mostly focussed on kava, lavender, saffron, probiotics, Galphimia glauca and valerian. Studies used varying dosages. Compared to herbal medicine studies, there were much fewer dietary supplement studies and homeopathic remedy studies, despite some of use of these by the general public. Conclusion Future research needs to investigate commonly used but less evaluated products (e.g. chamomile, St John’s Wort) and to evaluate products against or alongside conventional treatments to better reflect patient decision making.

DOI

https://doi.org/10.1080/09638237.2024.2408231

Type

Journal article

Journal

Journal of Mental Health

Publisher

Taylor & Francis Group

Publication Date

30/09/2024

Addresses

This review was linked to a project funded by the National Institute National Institute for Health and Care Research (NIHR) School for Primary Care Research (project reference 635).

Keywords

anxiety, herbal medicine, homeopathy, dietary supplements, over-the-counter

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