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Protocol for the mixed methods, Managing young people (aged 16–25) with Attention deficit hyperactivity disorder in Primary care (MAP) study: mapping current practice and co-producing guidance to improve healthcare in an underserved population
Attention deficit hyperactivity disorder (ADHD) is the most common neurodevelopmental disorder in children and adolescents, with an average worldwide prevalence of 5%. Up to 40% of young people continue to experience symptoms into adulthood. Young people with ADHD experience poorer outcomes tha…
Temporal trends in eating disorder and self-harm incidence rates among adolescents and young adults in the UK in the 2 years since onset of the COVID-19 pandemic: a population-based study
Background Self-harm and eating disorders share multiple risk factors, with onset typically during adolescence or early adulthood. We aimed to examine the incidence rates of these psychopathologies among young people in the UK in the 2 years following onset of the COVID-19 pandemic. Methods We conducte…
Management of asthma in primary care in the changing context of the COVID-19 pandemic: a qualitative longitudinal study with patients
Abstract Background: The COVID-19 pandemic dramatically affected asthma monitoring in primary care. Yet, patients’ views and experiences of managing their asthma and seeking help from primary care during the pandemic have not been explored. Aim: To investigate patients’ experiences of asthma manag…
Adherence to limiting weight-bearing activity in patients with diabetic foot ulcers: A qualitative study
Abstract Patients with diabetic foot ulcers are advised to limit weight-bearing activity for ulcers to heal. Patients often disregard this advice although the reasons are not yet fully understood. This study explored (1) patients' experiences of receiving the advice and (2) factors influencing adherence to the advi…
Association of Recent Fatherhood With Antidepressant Treatment Initiation Among Men in the United Kingdom
Abstract Importance There is some evidence that men may be at higher risk of depression directly following the birth of their child and that approximately 1 in 10 men will experience depression in the year after birth, but less is known about men’s antidepressant treatment during this time. Likewise, few direct c…
Unpromising Futures: Early-Career GPs’ Narrative Accounts of Meaningful Work during a Professional Workforce Crisis
Abstract Over the past few decades, the intensification and reorganisation of work have led to growing precarity, insecurity and uncertainty for employees, affecting even professionals tied to traditionally model employers. Doctors, in particular, have seen substantial changes to their work: having to work harde…
Why should we prioritise smoking cessation for people with mental health conditions?
Smoking is the single largest cause of preventable death and responsible globally for 7.7 million deaths in 2019. This is due to increased risk of cardiovascular disease, chronic obstructive pulmonary disease, type 2 diabetes, cancer, and blindness. Smoking is also associated with increased risk of developing mental…
Parental experiences of eczema advice in online parenting forums: Qualitative interview study
Background Parents of children with eczema are increasingly turning to online parenting forums for advice about managing childhood eczema. Little is known about how parents make sense of advice about eczema treatments in online forums, and how it affects their management of childhood eczema. Aim The ai…
Self-management of multiple long-term conditions: A systematic review of the barriers and facilitators amongst people experiencing socioeconomic deprivation
Abstract Background Multiple long-term conditions are rising across all groups but people experiencing socioeconomic deprivation are found to have a higher prevalence. Self-management strategies are a vital part of healthcare for people with long-term conditions and effective strategies are associated with imp…
Demographic characteristics, long-term health conditions and healthcare experiences of 6333 trans and non-binary adults in England: nationally representative evidence from the 2021 GP Patient Survey
Objective In order to address the lack of data on the health and healthcare needs of trans and non-binary adults, NHS England includes questions asking about both gender and trans status in its surveys to support quality improvement programmes. We used self-reported data from the GP Patient Survey to a…
The functions of self-harm in young people and their perspectives about future general practitioner-led care: A qualitative study
Background Self-harm in young people is a serious concern but a deeper understanding of the functions of self-harm in young people can tailor care and inform new clinical interventions to reduce repeat self-harm and suicide risk. General practitioners (GPs), as frontline healthcare professionals, have an imp…
Mental health services in response to the COVID-19 pandemic in high-income countries: protocol for a rapid review
Introduction The COVID-19 pandemic has caused disruptions to mental health services, forcing the rapid implementation of alternative ways of delivering services alongside a greater immediate, and continuously growing, demand across those services. The care and level of mental health service provided are…
Maternal and perinatal death surveillance and response: a systematic review of qualitative studies
Objective To understand the experiences and perceptions of people implementing maternal and/or perinatal death surveillance and response in low- and middle-income countries, and the mechanisms by which this process can achieve its intended outcomes. Methods In June 2022, we systematically searched…
Supportive care needs of men with prostate cancer: A systematic review update
Background Prostate cancer is highly prevalent and impacts profoundly on patients' quality of life, leading to a range of supportive care needs. Methods An updated systematic review and thematic synthesis of qualitative data using the Preferred Reporting Items for Systematic Reviews (PRISMA) reporting guidel…
Blood eosinophils to guide inhaled maintenance therapy in a primary care COPD population
Abstract Blood eosinophils are a potentially useful biomarker for guiding inhaled corticosteroid (ICS) treatment decisions in COPD. We investigated whether existing blood eosinophil counts predict benefit from initiation of ICS compared to bronchodilator therapy. We used routinely collected data from UK primar…
A descriptive cohort study of withdrawal from inhaled corticosteroids in COPD patients
Abstract Inhaled corticosteroid (ICS) therapy is widely prescribed without a history of exacerbations and consensus guidelines suggest withdrawal of ICS in these patients would reduce the risk of side effects and promote cost-effective prescribing. The study describes the prescribing behaviour in the United Kin…
Clinical relevance of double-arm blood pressure measurement and prevalence of clinically important inter-arm blood pressure differences in Indian primary care
Abstract Hypertension guidelines recommend measuring blood pressure (BP) in both arms at least once. However, this is seldom done due to uncertainties regarding measurement procedure and the implications of finding a clinically important inter-arm BP difference (IAD). This study aimed to provide insight in…
Performance of the imPulse device for the detection of atrial fibrillation in hospital settings
Background Atrial fibrillation (AF) increases thromboembolism and stroke risk; this can be reduced by oral anticoagulation, but only if AF is detected. A portable, point-of-care device, capable of accurately detecting and identifying AF, could reduce workload and diagnostic delay by minimizing need for follo…
A pragmatic effectiveness-implementation study comparing trial evidence with routinely collected outcome data for patients receiving the REACH-HF home-based cardiac rehabilitation programme
Background Cardiac rehabilitation for heart failure continues to be greatly underused worldwide despite being a Class I recommendation in international clinical guidelines and uptake is low in women and patients with mental health comorbidities. Methods Rehabilitation EnAblement in CHronic Heart Failure (R…
Incidence of postural hypotension recorded in UK general practice: an electronic health records study
Background Postural hypotension is a common condition associated with adverse outcomes in older adults. General practice plays an important role in identification of the condition. Aim To examine the incidence of postural hypotension between 2008 and 2018 in general practice and how trends vary by ag…
Latest news
New Handbook Offers Guidance for Supporting Loved Ones Facing Domestic Abuse
29 July 2025
A study funded by the NIHR School for Primary Care Research (SPCR) has led to the creation of a new Friends and Family Handbook, offering vital guidance for those supporting someone who may be experiencing domestic abuse.
SPCR IN Focus | World Hepatitis Day
28 July 2025
To mark this year’s World Hepatitis Day (28 July 2025), the NIHR School for Primary Care Research (SPCR) is highlighting projects that raise awareness of hepatitis and related health inequalities.
SPCR members awarded at SAPC ASM 2025
21 July 2025
SPCR colleagues were well represented at the SAPC Annual Scientific Meeting held in Cardiff this July, with several members receiving awards in recognition of their work in primary care research.