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‘We’re all doing different things’: Qualitative study exploring primary care practitioners’ perspectives of managing distress

Background: Distinguishing emotional distress from mental health problems such as anxiety and depression can be difficult for clinicians. Both commonly present and are managed in primary care. There are likely important differences in the management of emotional distress compared with depression/anxie…

Association of strong opioids and antibiotics prescribing with GP burnout: a retrospective cross-sectional study

Abstract Background Prescribing of strong opioids and antibiotics impacts patient safety, yet little is known about the effects GP wellness has on overprescribing of both medications in primary care. Aim To examine associations between strong opioid and antibiotic prescribing and practice- weighted…

Providing inclusive care and empowering people with dementia as a clinical pharmacist: a qualitative study of clinical pharmacist’s experiences

Abstract Objectives Dementia is a growing global health concern, significantly impacting primary care settings, where the majority of care for people with dementia is provided. Underserved and vulnerable groups, who often face disparities in access to care are at greater risk of this strain. Clinical pharmacists…

Trends in full-time working in general practice: a repeated cross-sectional study

Background There is little evidence and no agreement on what constitutes full-time working for GPs. This is essential for workforce planning, resource allocation, and accurately describing GP activity. Aim To clarify the definition of full-time working for GPs, how this has changed over time, and whether thes…

Exploring patient and professional perspectives on implementing pharmacogenomic testing in the UK primary care setting and estimating the cost-effectiveness: a mixed-methods study protocol

Abstract Introduction Pharmacogenomic testing could potentially reduce the number of adverse drug reactions and improve treatment outcomes through tailoring treatment to an individual’s genetic makeup. Despite its benefits and the ambitions to integrate into routine care, the implementation of pharmaco…

Risk factors for pancreatic cancer in electronic health records: an umbrella review of systematic reviews and meta-analyses

Background Pancreatic cancer has poor survival because of predominantly advanced-stage diagnosis. One strategy for improving outcomes is earlier identification, possibly achievable by enhanced surveillance or improved risk prediction modelling. This umbrella review updates previous evidence with a c…

A heterogeneity analysis of health-related quality of life in early adults born very preterm or very low birthweight across the sociodemographic spectrum

Abstract Preterm birth and very low birthweight (VP/VLBW) are associated with poorer health-related quality of life (HRQoL) outcomes extending into adulthood, yet it remains unclear how these effects differ across sociodemographic subgroups. This study aimed to identify heterogeneity in the association…

Practitioners’ views on the measurement and management of postural hypotension in general practice: a qualitative inquiry

Background: Postural hypotension (PH) is associated with cognitive decline, falls and allcause mortality, representing a substantial burden on the NHS. PH is often asymptomatic, making detection and treatment difficult. Currently, there is no systematic approach to measuring and managing PH in UK general pra…

Identifying novel biomarkers suitable for early detection of Intrathoracic cancers in primary care: a systematic review.

Review objectives Are there any novel biomarkers for detection and diagnosis of intrathoracic cancers that are suitable for use in primary care? To address this review question, we will identify and describe existing validated biomarkers for the detection/diagnosis of intrathoracic (primary lung/bronchus/trachea,…

Inter-arm blood pressure difference and cardiovascular risk estimation in primary care: a pilot study

Abstract Background Systolic inter-arm differences (IAD) in blood pressure (BP) contribute independently to cardiovascular risk estimates. This can be used to refine predicted risk and guide personalised interventions. Aim To model the effect of accounting for IAD in cardiovascular risk estimation in a primary care…

Blood test result communication in primary care: mixed-methods systematic review protocol

Abstract Background: After testing, ensuring test results are communicated and actioned is important for patient safety, with failure or delay in diagnosis the most common cause of malpractice claims in primary care worldwide. Identifying interventions to improve test communication from the decision to test thr…

Associations between burnout and career disengagement factors among general practitioners: a path analysis

Violence and Abuse towards General Practice Staff by Patients and the Public: A Scoping Review

Abstract Background General practice is the gatekeeper to secondary care in many countries. This unique role may expose general practice staff to violence and abuse by patients and the public, yet violence and abuse in secondary care receives more attention than that in general practice. Existing reviews on p…

Arm Based on LEg blood pressures (ABLE-BP): can systolic ankle blood pressure measurements predict systolic arm blood pressure? An individual participant data meta-analysis from the INTERPRESS-IPD Collaboration

Abstract Objectives To determine associations between arm and ankle systolic blood pressures (SBPs), develop and validate a multivariable model predicting arm SBP from ankle SBP, and investigate associations between ankle SBP, cardiovascular disease and mortality. Design Ankle-arm SBP differences were ex…

Identifying risks in dementia care: Insights from a qualitative study with clinical pharmacists

Introduction People with dementia experience complex healthcare needs. Clinical pharmacists play a crucial role in optimising medication management and ensuring patient safety within the primary care setting. However, little is known about the specific barriers and challenges they face when delivering demen…

The Views of Adult Weight Management Dietitians on Service Provision for People With Obesity and Severe Mental Illness and/or Learning Disability: A Qualitative Study

ABSTRACT Specialist adult weight management (AWM) services (tier 3) provide multidisciplinary support for people with obesity to manage their weight. Many people with severe mental illness (SMI)/learning disability also have obesity. This study explored the opinions of specialist AWM dietitians in the North-East a…

Multiple long-term conditions, loneliness and social isolation: A scoping review of recent quantitative studies

Abstract Background Multiple long-term conditions (MLTC), loneliness and social isolation are common in older adults. Recent studies have explored the association of MLTC with loneliness and social isolation. This scoping review aimed to map this current evidence and identify gaps in the literature. Methods…

Young people's priorities for the self-management of distress after stoma surgery due to inflammatory bowel disease: A consensus study using online nominal group technique

Abstract Introduction The aim of this study was to gain consensus among young people with a stoma due to inflammatory bowel disease (IBD) on the priorities for the content of an intervention for the self-management of stoma-related distress. The current identification and management of distress in yo…

Patterns and trends of medicinal poisoning substances: a population-based cohort study of injuries in 0–11 year old children from 1998–2018

Abstract Background There have been sharp increases in antidepressant and opioid prescriptions over the last 10 years, as well as increased over-the-counter medicine availability. However, the impact on childhood medicinal poisonings rates, particularly by socioeconomic deprivation is unclear. This study…

The reflexive imperative in the digital age: Using Archer’s ‘fractured reflexivity’ to theorise widening inequities in UK general practice

Abstract ‘Reflexivity’, as used by Margaret Archer, means creative self-mastery that enables individuals to evaluate their social situation and act purposively within it. People with complex health and social needs may be less able to reflect on their predicament and act to address it. Reflexivity is imperative in com…