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Tasmin Nasir Hamid

In 2015, the success of the SPCR funded TASMIN-SR trial (Target and self-management for the control of blood pressure in stroke and at risk groups), receiving over £241K from the School, resulted in the RCGP Research Paper of the Year Award for a publication in JAMA. Following this achievement, the TASMIN-H4 project (funded by the NIHR Programme Grant for Applied Research) was established and has just published its results in The Lancet. The research recommends that all GPs encourage patients with hypertension to monitor their blood pressure at home and report their readings back to the clinic. The study was led by Professor Richard McManus and conducted at the Universities of Oxford, Cambridge and Birmingham. Read the University of Oxford’s Press release.

Based on the results of the trial, researchers from the Universities of Oxford, Cambridge and Birmingham, assert that when GPs base their medication adjustments on regular blood pressure readings taken by patients at home, blood pressure is significantly lower after 12 months when compared with those who are managed exclusively in the clinic.

The NIHR-funded trial involved more than 1000 patients with poorly-controlled blood pressure, recruited through 142 general practices in England. The study was led by Oxford University’s Primary Care Clinical Trials Unit. 

Read the full press release here.

The earlier School funded TASMIN-SR project investigated the effects of self-monitoring in the lowering blood pressure amongst patients with hypertension. The results confirmed that among patients at high risk of cardiovascular disease, self-monitoring with self-titration of antihypertensive medication compared with usual care resulted in lower systolic blood pressure at 12 months.

The research was led by Professor Richard McManus from the University of Oxford's Nuffield Department of Primary Care Health Sciences and involved researchers from the universities of Birmingham, Cambridge, Central Lancashire, Southampton and UCL in the UK, and from the Vancouver Coastal Health Research Institute and the University of British Columbia in Canada.

JAMA publication: Effect of Self-monitoring and Medication Self-titration on Systolic Blood Pressure in Hypertensive Patients at High Risk of Cardiovascular Disease