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The School for Primary Care Research co-funded a study into type 2 diabetes which has produced the most detailed picture to date of the genetics underlying the condition.

Diabetes

More than 300 scientists from 22 countries collaborated on the study, which analysed the genomes of more than 120,000 people with ancestral origins in Europe, South and East Asia, the Americas and Africa.

Andrew Farmer, Professor of General Practice in the Nuffield Department of Primary Care Health Sciences,  working with colleagues from the Oxford Centre for Diabetes, Endocrinology and Metabolism, contributed data from a group of 200 patients who were recruited from 12 local practices in a study looking at the prevalence of monogenic diabetes. The findings of this community-based study in Oxfordshire were published in 2011 in Diaebetologia.

The findings of the broader study, published in Nature, identify several potential targets for new diabetes treatments, but also reveal the complexity of the disease that needs to be addressed by efforts to develop more personalised strategies for treatment and prevention.

Read the full story here.

Podcasts and blogs posted by the team can be found here.